CANNABINOIDS: Cannabinoids are currently used to reduce nausea and vomiting during chemotherapy, to improve appetite in people with HIV/AIDS, and to treat chronic pain and muscle spasms (among other uses). Cannabinoids are also currently in various stages of clinical trials to treat epilepsy, sclerosis, lupus, schizophrenia, and a variety of other disorders. A sustained-release topical mode of application has significant potential to help treat these disorders, and many others as well. We have demonstrated that cannabinoid-loaded Nanopods™ reduce the size and severity of skin lesions associated with lupus. Due to the regulatory environment and to the specialized nature of the various derivatized forms of cannabinoids, Zylö will likely out-license the development of cannabinoid-related product candidates.

Adam Friedman, MD talks to host Joshua Zeichner, MD about how cannabis might benefit dermatology. While cannabis has gotten a lot of attention in treating side effects of cancer treatments, pain, and epilepsy, its potential in dermatology is just beginning to be researched. Dr. Friedman discusses what's currently known, how it could be used to treat inflammation, itch, and pain, and the need to develop a delivery system for topical use.